Pure Colombian Cocaine |Cocaine hydrochloride

High-purity Cocaine Hydrochloride (Cocaine HCl) is a chemically purified, pharmaceutical-grade form of  Pure Colombian Cocaine, used in very specific medical and forensic contexts. Here’s a detailed breakdown:

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Chemical Information

• Chemical name: Cocaine hydrochloride

• Chemical formula: C₁₇H₂₂ClNO₄

• Molecular weight: ~339.81 g/mol

• Form: White crystalline powder (in high-purity form)

• Solubility: Highly soluble in water

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Medical Uses

Despite its reputation as a street drug, cocaine HCl has legitimate medical applications:

1. Local anesthetic (especially in ear, nose, and throat [ENT] surgery):

   • Cocaine is a powerful topical anesthetic and vasoconstrictor.

   • Example: Applied to nasal mucosa during surgery to reduce bleeding and numb the tissue.

2. Ophthalmic use: Occasionally used in eye diagnostics to test for nerve damage (Horner’s syndrome), although this is rare today.

3. Forensic use:

   • Used as a reference standard for lab testing.

   • Helps law enforcement verify seized substances.

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Mechanism of Action (How It Works)

Cocaine works primarily by blocking the reuptake of neurotransmitters in the brain, especially:

• Dopamine

• Norepinephrine

• Serotonin

This leads to:

• Accumulation of neurotransmitters at synapses.

• Intense stimulation of the central nervous system (CNS).

Additionally, it:

• Blocks voltage-gated sodium channels, which is how it causes local anesthesia (blocks nerve signals).

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Effects on Human and Animal Bodies

In Humans (When Not Used Medically)

Short-term effects:

• Euphoria

• Increased energy

• Alertness

• Loss of appetite

• Increased heart rate and blood pressure

Adverse effects (even in medical use at high doses):

• Anxiety, paranoia

• Irregular heartbeat

• Seizures

• Risk of stroke or heart attack

• Addiction (very high potential)

Chronic use causes:

• Neurotoxicity

• Nasal septum damage (if snorted)

• Cardiovascular damage

• Psychiatric symptoms

🐁 In Animals

In laboratory studies:

• Rodents and primates exhibit hyperactivity, increased aggression, and addiction patterns.

• Cocaine affects dopaminergic reward pathways similarly to humans.

• High doses can lead to convulsions, respiratory failure, or death.

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Legal Status

• Schedule II controlled substance in the U.S. (legal for limited medical use, high abuse potential).

• Strictly regulated worldwide.